Study

Fluoxetine and Divalproex: Treatment Correlates In IED

Principal Investigator

Emil F. Coccaro, M.D.

Description

Anger and aggression are everywhere - on the road, in the schools, at little league games. Anger can be used constructively at times. It can give us energy when we need to fight back if physically attacked. However, for most situations it merely clouds our judgment and creates extra stress. If anger prompts aggressive behavior toward other people, it can permanently harm relationships - especially with those we love. If anger is a problem for you, you may be suffering from Intermittent Explosive Disorder (IED) and may be eligible to take part in a research study. Dr. Emil Coccaro a Psychiatrist Internationally known in the field of IED is conducting a research study called Fluoxetine and Divalproex: Treatment Correlates In IED to test if treatment with Fluoxetine (Prozac), Divalproex (Depakote), or placebo (a sugar pill) can reduce the symptoms of IED.

Eligibility

  • Have problems with anger, temper outbursts, being irritable, getting in trouble at work or at home because of impulsive/aggressive behavior.
  • Between the ages of 21 and 55.
  • Meet other eligibility requirements as outlined by the research protocol.
  • Only for fMRI: Have had no brain, heart, or other surgeries that would entail the insertion of metal on a permanent basis.
  • Only for fMRI: Women must not be pregnant, therefore a pregnancy test will be required.

    Duration

    16 (or 17) Weekly visits up to 4 months.

    Compensation

    Up to $715.

    Contact

    Cindy Bogue
    (773) 70-ANGER that's (773) 702-6437
    anger@yoda.bsd.uchicago.edu