Paul Vezina, PhD


5841 S. Maryland Ave., MC 3077, Rm J131
Chicago, Illinois 60637
Phone: 773-702-2890
Office: 773-702-2891
Lab: 773-702-2899
Fax: 773-702-0857

Lab Website:

Education & Training

  • Concordia University, Montreal, Canada, PhD, 1988
  • Postdoctoral Research, Neuropharmacologie, Collège de France, Paris, France, 1988-1990

Research Interests

  • Basal ganglia and the generation of appetitive behaviors
  • Signaling pathways underlying drug-induced neuronal plasticity
  • Neurobiology and neuropharmacology


  • Director, NIDA Training Program (T32 DA007255, NIDA)
  • Neuropsychopharmacology, NURB 32800, Winter Quarter
  • Neurobiology of Disease, NURB 34600, Winter Quarter, Course Director: Dr. C. Gomez
  • Perspectives in Drug Abuse, PHARM 32900, Spring Quarter, Course Director: Dr. H. de Wit

Society Memberships

  • American College of Neuropsychopharmacology
  • College on Problems of Drug Dependence
  • European Behavioural Pharmacology Society
  • Society for Neuroscience

Representative Publications (from last year)

  • Loweth JA, Svoboda R, Austin JD, Guillory AM, Vezina P. The PKC inhibitor Ro31-8220 blocks acute amphetamine-induced dopamine overflow in the nucleus accumbens. Neuroscience Letters 2009; 455: 88-92.
  • Singer BF, Tanabe LM, Gorny G, Jake-Matthews C, Li Y, Kolb B, Vezina P. Amphetamine-induced changes in dendritic morphology in rat forebrain correspond to associative drug conditioning rather than nonassociative drug sensitization. Biological Psychiatry 2009, in press.
  • Bryant CD, Graham ME, Distler MG, Munoz MB, Li D, Vezina P, Sokoloff G, Palmer AA. A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine. Psychopharmacology 2009; 203: 703-711.
  • Vezina P, Leyton M. Conditioned cues and the expression of sensitization in animals and humans. Neuropharmacology 2009; 56: 160-168.
  • Loweth JA, Baker LK, Guptaa T, Guillory AM, Vezina P. Inhibition of CaMKII in the nucleus accumbens shell decreases enhanced amphetamine intake in sensitized rats. Neuroscience Letters 2008; 444: 157-160.
  • Kim WY, Vezina P, Kim J-H. Blockade of group II, but not group I, mGluRs in the rat nucleus accumbens inhibits the expression of conditioned hyperactivity in an amphetamine-associated environment. Behavioural Brain Research 2008; 191: 62-66.
  • Vezina P. Hot Topics: Evidence that dopamine response to amphetamine sensitizes in humans. Neuropsychopharmacology Reviews 2008; 33: 206-207.

Current Editorial Boards

  • Neuroscience and Biobehavioral Reviews
  • Neuroscience and Neuroeconomics
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry

Other Activities

  • Director, NIDA Drug Abuse Research Program