Sarah Keedy, Ph.D.

Assistant Professor, of Psychiatry & Behavioral Neurosciences
Director, Cognition-Emotion Neuroscience Laboratory

Address: 5841 S. Maryland Ave., MC 3077, Rm L-466C
Phone: 773-834-7178
Fax: 773-834-4536

 Laboratory Website: http://cnpru.bsd.uchicago.edu/keedy.html

 Education & Training

  • Rosalind Franklin University of Medicine and Science, Ph.D. (Clinical Psychology), 2004
  • Jesse Brown Veterans Administration Medical Center, Internship, 2003-2004
  • University of Illinois at Chicago, Post-doctoral Fellowship, 2004-2006
  • Illinois Licensed Clinical Psychologist, 2007-present

Clinical Interests

  • Brief, problem-focused therapy for patients with major mental illness
  • Acquired cognitive impairment / brain injury
  • Diagnostic interviewing / symptom assessment

Research Interests

  • Identify neurocognitive dysfunction associated with acute psychosis in schizophrenia or bipolar disorder, whether first episode or exacerbation of chronic illness
  • Examine neurocognitive effects of antipsychotic medication
  • Assess contributions of top down vs. bottom up brain processes for sensory information flow, for relevance to hallucinations or psychotic illness generally
  • Assess the dimensional nature of the phenomenology of hallucinations, and determine which may be most relevant to neurocognitive dysfunction, treatment responsiveness, etc., across psychotic disorders

Teaching

  • Clinical Psychology Internship Clinical Research Faculty Seminar, “Early Research Career Development,” 2012-present
  • Guest Lecturer, MS-II Human Behavior in Health and Illness, “Behavioral Neuroimaging,” 2012-present

Society Memberships

  • Biological Psychiatry, 2011 – present
  • Cognitive Neuroscience Society, 2011-present
  • Organization for Human Brain Mapping, 2011-present
  • International Early Psychosis Association, 2005-present
  • Society for Neuroscience, 2004-present
  • American Psychological Association, 1995-present

Selected Publications (Since 2009)

Keedy SK, Ebens CL, Keshavan MS, Sweeney JA (2006). Functional magnetic resonance imaging studies of eye movements in first-episode schizophrenia: Smooth pursuit, visually guided saccades, and the oculomotor delayed response task. Psychiatry Research: Neuroimaging 146, 199-211.

Keedy SK, Marlow-O’Connor M, Beenken B, Dorflinger J, Abel M, Erwin R (2007). Noradrenergic antagonism of the P13 and N40 components of the rat auditory evoked potential. Psychopharmacology 190(1), 117-125.

Sweeney JA, Luna B, Keedy SK, McDowell JE, Clementz BA (2007). fMRI studies of eye movement control: Investigating the interaction of cognitive and sensorimotor brain systems. NeuroImage 36 Suppl 2, T54-T60.

Keedy SK, Rosen C, Khine T, Rajarethinamb R, Janicak PG, Sweeney JA (2009). An fMRI study of visual attention and sensorimotor function before and after antipsychotic treatment in first episode schizophrenia. Psychiatry Research: Neuroimaging, 172(1), 16-23.

Rosen C, Marvin R, Reilly JL, DeLeon O, Harris MSH, Keedy SK, Solari H, Weiden P, Sweeney JA. (2012). Phenomenology of first episode psychosis in schizophrenia, bipolar disorder, and unipolar depression:  A comparative analysis.  Clinical Schizophrenia & Related Psychosis 6(3), 145-151A.

Lencer R, Keedy SK, Reilly JL, Harris MSH, Sprenger A, Sweeney JA (2011).  Altered transfer of visual motion information to parietal association cortex in untreated first-episode psychosis:  Implications for pursuit eye tracking. Psychiatry Research: Neuroimaging, 194(1), 30-38.

Lu LH, Zhou XJ, Keedy SK, Reilly JL, & Sweeney JA. (2011). White matter microstructure in untreated first episode bipolar disorder with psychosis: Comparison with schizophrenia. Bipolar Disorders, 13, 604-613.

Lu LH, Zhou XJ, Fitzgerald J, Keedy SK, Reilly JL, Passarotti AM, Sweeney JA, & Pavuluri MN (2012). Microstructure abnormalities of white matter differentiate the pediatric and adult onset bipolar disorder.  Bipolar Disorders 14(6), 597-606.

Ethridge LE,  Hamm JP, Shapiro JR, Summerfelt AT, Keedy SK, Stevens MC, Pearlson G, Tamminga CA, Boutros NN, Sweeney JA, Keshavan MS, Thaker G, Clementz BA (2012).  Neural activations during auditory oddball processing discriminating schizophrenia and psychotic bipolar disorder. Biological Psychiatry 72(9), 766-774.

Ford J, Mathalon D, Roach B , Keedy S, Reilly J, Gershon E, Sweeney J (in press).  Corollary discharge dysfunction in psychosis. Schizophrenia Bulletin.