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Ya-Ping Tang Ph.D.
Phone: 773-834-5151
Email: yptang@yoda.bsd.uchicago.edu
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Office: Knapp Center R020
Specialty: Neurobiology of learning and memory, mouse genetics,                              neurobiology of mental disease


About:

1982, Bachelor’s degree in Medicine, Luchow Medical College, China, majoring in Medicine

1989, Master’s degree in Science, Shanghai Second Medical University, China majoring in Neurobiology

1998, Ph.D., Nagoya University, Japan, majoring in Molecular Biology and Neurobiology

2001, Post-doctor, Princeton University, majoring in Neurobiology and Mouse Genetics

2001, to now, Assistant Professor, Department of Psychiatry, The University of Chicago, majoring in Neurobiology

 

Selected Publications:

Tang, Y-P, Shimizu, E, Dube, G, Rampon, C, Keercher, G, Zhou, M, Liu, G and Tsien, JZ (1999) Genetic enhancement of learning and memory in mice. Nature 401: 63-69.


Tang, Y-P*, Rampon, C*, Goodhouse, J, Shimizu, E, Kyin, M and Tsien, JZ (2000) Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice. Nat Neurosci 3: 238-244.


Rampon, C, Jiang, CH, Dong, H, Tang, Y-P, Lockhart, DJ, Schultz, PG, Tsien, JZ and Hu, Y (2000) Effects of environmental enrichment on gene expression in the brain. Proc Natl Acad Sci USA 97: 12880-12884.



Tang, Y-P*, Shimizu, E*, Rampon, C and Tsien, JZ (2000) NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation. Science 290:1170-1174.



Feng, R, Rampon, C, Tang, Y-P, Shrom, D, Jin, J, Kyin, M, Sopher, B, Miller, MW, Ware, CB, Martin, GM, Kim, SH, Langdon, RB, Sisodia, SS, Tsien, JZ (2001) Deficient neurogenesis in presenilin-1 forebrain knockout mice prevents clearance of hippocampal memory traces. Neuron 32: 911-926.



Wang, H, Shimizu, E, Tang, Y-P, Cho, M, Kyin M, Zuo W, Robinson, DA, Alaimo, AP, Zhang Cc, Morimoto, H, Zhuo,M, Feng, R, Shokat, KM, Tsien, JZ (2003) In vivo conditional protein knockout for temporal analysis of memory consolidation in mice. Proc Natl Acad Sci USA 100: 428742-92.


Lazaroy, O, Robinson, J, Tang, Y-P, Hairston, IS, Korade-Mirnics, Z., Lee, V, Hersh, LB, Sapolsky, RM, Mirnics, K, and Sisodia, SS (2005) Environmental enrichment reduces a-b levels and amyloid deposition in transgenic mice. Cell. 120: 701-713.



Chen, Q, Nakajima, A, Meacham, C, Tang, Y-P (2006) Elevated CCKergic tone constitutes an important molecular/neuronal mechanism for the expression of anxiety in the mouse. Proc Natl Acad Sci USA 103: 3881-3886.



Kim SH, Tang, Y-P, Sisodia SS (2006) A-beta star: a light onto synaptic dysfunction?  Nat Med 12: 760-761.

*: these authors contributed equally to the work.




 

 

 

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