Publications: 2010 - 2011

Hamidovic, A. A.M. Dlugos, A.A. Palmer, H, de Wit (2010) Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of d-amphetamine – an exploratory pharmacogenetic study using healthy volunteers. Behavior Genetics 40, 255-260. PMID: 20091113

Childs, E., N.T. Van Dam, H. de Wit (2010) Effects of acute progesterone administration upon responses to acute psychosocial stress in men. Experimental Clinical Psychopharmacology, 18, 78-86. PMID: 20158297

Dlugos, A.M., A. Hamidovic, C.A. Hodgkinson, D. Goldman, A.A. Palmer, H. de Wit (2010) More aroused, less fatigued: FAAH gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology, 35, 613-22. PMID: 19890266

Porcu, P, T.K. O’Buckley, S.E. Alward, K.A. Grant, H. de Wit, A.L. Morrow (2010) Differential effects of ethanol on serum GABAergic 3a,5a/3a,5b neuroactive steroids in mice, rats, Cynomolgus monkeys and humans. Alcoholism: Clinical Experimental Research, 34, 432-42 PMID: 20028362

McCloskey, M., A.A. Palmer, H. de Wit (2010) Is self-reported liking of d-amphetamine related to impulsivity? Psychopharmacology, 208, 201-9. PMID: 19936714

Hamidovic, A., E. Childs, M. Conrad, A. King, H. de Wit (2010) Stress-induced changes in mood and cortisol release predict mood effects of amphetamine. Drug and Alcohol Dependence 109 175-180. PMC2875349

Yang, A., A.A. Palmer, H. de Wit (2010) Genetics of caffeine consumption and caffeine response. Psychopharmacology, 211, 245–257. PMID: 20532872

Childs, E., A.M. Dlugos, H. de Wit (2010) Cardiovascular, hormonal, and emotional responses to the TSST in relation to sex and menstrual cycle phase. Psychophysiology, 47 550–55. PMID: 20070572

Hamidovic, A. A.M. Dlugos, A.A. Palmer, H, de Wit (2010). Catechol-O-methyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine. Psychiatric Genetics, 25, 85-92. PMC2875066

Childs, E., H. de Wit (2010). Acute psychosocial stress increases cigarette craving and smoking pleasure. Nicotine and Tobacco Research, 12, 449-453. PMC2847070

Vaughn, L, Denning, G, Stuhr, K., de Wit, H., Hill, M.N., Hillard, C.J. (2010). Endocannabinoid signaling: Has it got rhythm? British Journal of Pharmacology, 160, 530-43. PMID: 20590563

Lejuez, C.W., J.R. Magidson, S.H. Mitchell, R. Sinha, M. Stevens, H. de Wit. (2010). Behavioral and biological indicators of impulsivity in the development of alcohol use disorders. Alcoholism: Clinical and Experimental Research, 34, 1334- 45. PMID: 20491733

Mueller, D. and H. de Wit (2011). Conditioned place preference in rodents and humans. Neuromethods, 50, 133-152. Ballard, M., H. de Wit (2011). Combined effects of acute, very-low-dose ethanol and delta(9)- tetrahydrocannabinol in healthy human volunteers. Pharmacology, Biochemistry and Behavior, 97, 627-31. PMC3018238

Mahler, S.V., H de Wit (2010). Cue-Reactors: Individual differences in cue-induced craving after food or smoking abstinence. PLoS ONE, 5:e15475 PMID: 21085667

Bedi, G., D. Hyman, H. de Wit (2010). Is ecstasy an ‘empathogen’? MDMA increases social feelings but blunts identification of negative emotions in others. Biological Psychiatry, 68, 1134-40. PMID: 20947066

Bedi, G., K.L. Preston, D.H. Epstein, S.J. Heishman, G.F Marrone, Y. Shaham, H. de Wit (2011) Incubation of cue-induced cigarette craving during abstinence in human smokers. Biological Psychiatry 69, 708-11 PMID: 20817135

Wardle, M., K. Cederbaum, H. de Wit (2010) Quantifying talk: Developing reliable measures of verbal productivity. Behavior Research Methods 43:168-178 PMID: 21287128

Dlugos, A.M., A. Hamidovic, C.A. Hodgkinson, S. Pei-Hong, D. Goldman, A.A. Palmer, H. de Wit (2011) OPRM1 gene variants modulate amphetamine-induced euphoria in humans. Genes, Brain and Behavior 10, 199-209 PMID: 2102937

King, A, H. de Wit, P. McNamara, D.-C. Cao (2011). Stimulant and sedative alcohol responses and relationship to future drinking. Archives of General Psychiatry, 68, 389-399. PMID: 21464363

Ballard, M.E., D.A. Gallo, H. de Wit (2011) Psychoactive drugs and false memory: Comparison of dextroamphetamine and delta(9)-tetrahydrocannabinol on false recognition. Psychopharmacology. PMID: 21647577 Wardle, M., M. Munafo, H. de Wit (in press) Effect of social stress during acute nicotine abstinence. Psychopharmacology. PMID: 21234550

Childs, E., S. O’Connor, H. de Wit (in press) Bidirectional interactions between acute psychosocial stress and acute IV alcohol. Alcoholism: Clinical and Experimental Research. Wignall, N. H. de Wit (2011) (in press) Effects of nicotine on cognition and behavioral inhibition in healthy nonsmokers. Experimental Clinical Psychopharmacology. 19,183-91. PMID: 21480731

Wardle, M.C., H. de Wit (in press) Effects of amphetamine on responses to positive emotional stimuli. Psychopharmacology.

Wardle, M.C., A. Yang, H. de Wit(in press) Effects of amphetamine on post-error slowing in humans. Psychopharmacology.

Publications: 2006 - 2009

Terner, J. M., & de Wit, H. (2006). Menstrual cycle phase and responses to drugs of abuse. Drug and Alcohol Dependence, 84, 1-13.

Reynolds, B., Ortengren, A., Richards, J. B., & de Wit, H. (2006). Dimensions of impulsive behavior: Personality and behavioral measures. Personality and Individual Differences, 40, 305-315.

Acheson, A., Mahler, S. V., Chi, H., & de Wit, H. (2006) Differential effects of nicotine on alcohol consumption in men and women. Psychopharmacology, 186(1):54-63.

King, A., Munisamy, G., de Wit, H. & Lin, S. (2006) Attenuated cortisol response to alcohol in heavy social drinkers. International Journal of Psychophysiology, 59, 203-209.

Reynolds, B., Richards, J. B., & de Wit, H. (2006) Acute-alcohol effects on the Experiential Discounting Task (EDT) and a question-based measure of delay discounting. Pharmacology, Biochemistry and Behavior, 83(2):194-202

de Wit, H., Vicini, L., Haig, G., Hunt, T., & Feltner, D. (2006) Evaluation of the abuse potential of pagoclone, a partial GABA a agonist. Journal of Clinical Psychopharmacology, 26(3):268-73.

Acheson A., Farrar A.M., Patak M., Hausknecht, K.A., Kieres, A.K., Choi, S. de Wit H., Richards, J.B. (2006) Nucleus accumbens lesions decrease sensitivity to rapid changes in the delay to reinforcement. Behav Brain Research, 173, 217-228.

Flanagin, B. A., de Wit, H., & Cook, Jr, E. H. (2006) Association study of the brain-derived neurotrophic factor Val66Met polymorphism and amphetamine response. Neuropsychiatric Genetics, 141B(6), 576-583.

Lott, D. C., Kim, S. J., Cook, E. H., & de Wit, H. (2006) Serotonin transporter genotype and acute subjective response to amphetamine. American Journal on Addictions, 15(5):327-35.

King, A., de Wit, H., Riley, R. C., Cao, D., Niaura, R., & Hatsukami, D. (2006) Efficacy of naltrexone in smoking cessation: A preliminary study and an examination of sex differences. Nicotine and Tobacco Research, 8(5):671-82.

Acheson, A., Reynolds, B., Richards, J. B., & de Wit, H. (2006) Diazepam impairs behavioral inhibition but not delay discounting or risk taking in healthy adults. Experimental and Clinical Psychopharmacology, 14(2):190-8.

Childs, E., Vicini, L., & de Wit, H. (2006) Responses to the Trier Social Stress Test (TSST) in single versus grouped participants. Psychophysiology, 43(4):366-71.

de Wit, H., Vicini, L., Childs, E., Sayla, M., Terner, J. (2006) Does stress reactivity or response to d-amphetamine predict progression to smoking in young adults? A preliminary study. Pharmacol Biochem Behav, 2007 Feb;86(2):312-9

White, T.L., Grover, V.K., de Wit, H. (2006) Cortisol effects of d-amphetamine relate to traits of fearlessness and aggression but not anxiety in healthy humans. Pharmacol Biochem Behav, 85, 123-131.

Childs, E., & de Wit, H. (2006) Subjective, behavioural and physiological effects of acute caffeine administration in light, non-dependent caffeine users. Psychopharmacology, 185(4):514-23.

Hariri, A.R., Brown, S.M., Williamson, D.E., Flory, J.D., de Wit, H., S.B. Manuck (2006) Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activity. The Journal of Neuroscience, 26, 13213-7.

de Wit, H., J.D. Flory, A. Acheson, M. McCloskey, S.B. Manuck. (2007) IQ and Nonplanning Impulsivity are independently associated with delay discounting in middle-aged adults. Personality and Individual Differences, 42, 111-121.

Dlugos, A., C. Freitag, C. Hohoff, J. McDonald, E.H. Cook, J. Deckert, H. de Wit (2007) Norepinephrine transporter gene variation modulates acute response to d-amphetamine. Biological Psychiatry 61, 1296-1305.

Acheson, A., Richards, J.B., de Wit H. (2007) Effects of sleep deprivation on impulsive behaviors in men and women. Physiology and Behavior, 91, 579-587.

White, T.L., C. W. Lejuez and H. de Wit (2007) Personality and gender differences in effects of d-amphetamine on risk-taking. Journal of Clinical and Experimental Psychopharmacology, 15, 599-609.

Childs E, de Wit H. (2008) Enhanced mood and psychomotor performance by a caffeine-containing energy capsule in fatigued individuals. Exp Clin Psychopharmacol, 16, 13-21.

Hamidovic, A., Kang, U., de Wit, H. (2008) Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers. Journal of Clinical Psychopharmacology, 28, 45-51.

Childs A., C. Hohoff, C., J. Deckert, X. Ke, J. Badner, H. de Wit (2008) Association between A1, A2a and DRD2 receptor gene polymorphisms and caffeine-induced anxiety. Neuropsychopharmacology, 33(12), 2791-2800.

Phan, K.L., M. Angstadt, J. Golden, I. Onyewuenyi, A. Popovska, H. de Wit (2008) Cannabinoid modulation of amygdala reactivity to social signals of threat in humans. J Neurosci, 28, 2313–2319.

Acheson, A., H. de Wit (2008) Bupropion improves attention but does not affect impulsive behavior in healthy men and women. J Exp Clin Psychopharmacol, 16, 113-123.

Miczek, K.A., H. de Wit (2008) Challenges for translational psychopharmacology research - Some basic principles. Psychopharmacology, 199, 291-301.

Bornovalova M.A., Cashman-Rolls A., O'Donnell J.M., Ettinger K., Richards J.B., de Wit H, Lejuez CW (2008) Risk taking differences on a behavioral task as a function of potential reward/loss magnitude and individual differences in impulsivity and sensation seeking. Pharmacol Biochem Behav, [Epub ahead of print].

White, T.L., C.W. Lejuez, H. de Wit (2008) Test-retest characteristics of the Balloon Analogue Risk Task (BART). Exp and Clin Psychopharmacol, 16, 565-570.

Childs, E., H. de Wit (2009) Hormonal, cardiovascular and subjective responses to acute stress in smokers. Psychopharmacology, 203, 1-12.

de Wit, H. (2009) Impulsivity as a determinant and consequence of drug use: A review of underlying processes. Addiction Biology, 1, 22-31.

Childs, E., H. de Wit (in press) Amphetamine-induced place preference in humans. Biological Psychiatry, [Epub ahead of print].

Hamidovic, A., H. de Wit (in press) Sleep deprivation increases smoking. Pharmacology, Biochemistry and Behavior, [Epub ahead of print].

de Wit, H. and L. Phan (in press) "Positive reinforcement theories of drug use." In: Substance Abuse and Emotion. Ed. Jon D. Kassel, American Psychological Association, Washington DC.

de Wit, H. and S. Mitchell (in press) "Drug Effects on Delay Discounting." In: Impulsivity: The behavioral and neurological science of discounting. Eds: G. J. Madden, W. K. Bickel, & T. S. Critchfield American Psychological Association, Washington DC.