We are currently supported to study the EEG and behavioral effects of neuropeptides administered to the olfactory epithelium in human volunteers. We have ongoing psychopharmacological experiments with insulin, corticotropin-releasing factor, oxytocin, and vasopressin. In parallel with this work, we are engaged in a rigorous examination of the neurophysiological correlates of neuropeptide effects on the brain, as well as of mental processing of emotion-relevant stimuli, such as emotional faces. This work includes multimodal imaging (scalp and intracranial EEG and fMRI). Our goal is to develop novel therapeutic and prognostic tools for the treatment of neurotic disorders. For more information, contact Royce Lee, MD, or visit my website.