Kristen C. Jacobson., Ph.D

Associate Professor
Associate Director of the Clinical Neuroscience and Psychopharmacology Research Unit (CNPRU)
Associate Director of Twin Programs

5841 S. Maryland Ave., MC 3077, Rm L-466D
Chicago, Illinois 60637
Phone: 773-834-0265
Fax: 773-834-4536

Laboratory Website:

Education & Training

  • A.B., Cornell University, Psychology & English, 1986-1990
  • M.S., Pennsylvania State University, Human Development & Family Studies, 1994
  • Ph.D., Pennsylvania State University, Human Development & Family Studies, 1999
  • Postdoctoral Scholar, Virginia Institute for Psychiatric & Behavioral Genetics, Virginia Commonwealth University, 1999-2000

Research Interests

  • The development of antisocial behavior over the life span
  • Behavioral genetics in ecological context
  • Gene x Environment interactions
  • Environmental influences on genetic and biological processes


  • Course Director, Multidisciplinary Approaches to Psychiatric and Behavioral Genetics, PSYC 46900, Winter and Spring quarters, 2009.
  • Co-Director, Research Training in Psychiatry, year-long course for Psychiatry Residents, 2006 – present.

Society Memberships

  • Behavior Genetics Association (BGA)
  • International Society for Twin Studies (ISTS)
  • American Psychopathological Association (APPA)
  • Society for Research on Adolescence (SRA)
  • American Psychological Association (APA)

Selected Publications

  • Jacobson, K.C. (forthcoming). From neighborhoods to neurons and beyond. Psychological Science Agenda, April, 2009.
  • Jacobson, K.C., Beseler, C.L., Su, J., Faraone, S.V., Glatt, S.J., Kremen, W.S., Lyons, M.J., & Tsuang, M.T. (2008). Ordered subsets linkage analysis of antisocial behavior in substance use disorder among participants in the Collaborative Study on the Genetics of Alcoholism. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B, 1258-1269.
  • Kendler, K.S., Jacobson, K.C., Myers, J.M., & Eaves, L.J. (2008). A genetically informative developmental study of the relationship between conduct disorder and peer deviance in males. Psychological Medicine, 7, 1001-1011.
  • Kremen, W.S., Jacobson, K.C., Lyons, M.J., Xian, H., Eisen, S.A., Eaves, L.J., & Tsuang, M.T. (2007). Genetics of verbal working memory processes: A twin study of middle-aged men. Neuropsychology, 21, 561-580.
  • Baker, L.A., Jacobson, K.C., Raine, A., Lozano, D.I., & Bezdjian, S.J. (2007). Genetic and environmental bases of childhood antisocial behavior: A multi-trait multi-method twin study. Journal of Abnormal Psychology, 116, 219-235.
  • Coccaro, E.F., & Jacobson, K.C. (2006). PennTwins: A population based cohort for twin studies. Twin Research and Human Genetics, 9, 998-1005.
  • Neale, M.C., Jacobson, K.C., & Røysamb, E. (2006). Multivariate genetic analysis of sex-limitation in human populations. Twin Research and Human Genetics, 9, 481-489.
  • Jacobson, K.C. (2005). Genetic influence on the development of antisocial behavior. In K. Kendler & L. Eaves (Eds) New Directions for Psychiatric Genetics (pp. 197-232). Washington, DC: American Psychiatric Press, Incorporated.
  • Jacobson, K.C. (2005). The genetic basis of substance use and abuse. In R. Stohler & W. Rossler (Eds.) Bibliotheca Psychiatrica, Vol. No. 171, Special Issue: Dual Diagnosis (pp.15-30). Basel, Switzerland: Karger Publications.
  • Jacobson, K.C. (2005). Gene-environment interaction. In B.S. Everitt & D.C. Howell (Eds.) Encyclopedia of Statistics in Behavioral Science (Wiley Series in Probability and Statistics, Volume 2, S. Purcell, Volume Editor, pp. 698-701). Chichester, England: John Wiley & Sons, Ltd.
  • Khan, A.A., Jacobson, K.C., Gardner, C.O., Prescott, C.A., & Kendler, K.S. (2005). Personality and comorbidity of common psychiatric disorders. British Journal of Psychiatry, 186, 190-196.
  • Kendler, K.S., Jacobson, K.C., Prescott, C.A., & Neale, M.C. (2003). The specificity of genetic and environmental risk factors in men for the illicit use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates. American Journal of Psychiatry, 160(4), 687-695.
  • Jacobson, K.C., Prescott, C.A., & Kendler, K.S. (2002). Sex differences in genetic and environmental influences on antisocial behavior from childhood to adulthood. Development and Psychopathology, 14, 395-416.
  • Jacobson, K.C., & Crockett, L.J. (2000).  Parental monitoring and adolescent adjustment: An ecological approach.  Journal of Research on Adolescence, 10, 65-97.
  • Jacobson, K.C., Prescott, C.A., Neale, M. C., & Kendler, K.S. (2000). Cohort differences in genetic and environmental influences on retrospective reports of conduct disorder among adult male twins. Psychological Medicine, 30, 775-787.
  • Jacobson, K.C., & Rowe, D.C. (2000). Nature, nurture, and the development of criminality. In J. F. Sheley (Ed.) Criminology: A contemporary handbook (3rd Edition). Wadsworth Publishing Company.
  • Jacobson, K.C., & Rowe, D.C. (1999).  Genetic and environmental influences on the relationships between family connectedness, school connectedness, and adolescent depressed mood: Sex differences.  Developmental Psychology, 35, 926-939.
  • Rowe, D.C., Almeida, D.M., & Jacobson, K.C. (1999). School context and genetic influences on aggression in adolescence. Psychological Science, 10, 277-280.
  • Rowe, D.C., Jacobson, K.C., & Van den Oord, E. J. C. G. (1999).  Genetic and environmental influences on vocabulary IQ: Parental education as moderator.  Child Development, 70, 1151-1162.
  • Jacobson, K.C., & Rowe, D.C. (1998).  Genetic and shared environmental influences on adolescent body mass index: Interactions with race and sex.  Behavior Genetics, 28, 265-278.

Invited Presentations

  • From Neighborhoods to Neurons and Beyond: Factors Associated with Adolescent Problem Behavior. Annual meeting of the Midwestern Psychological Association, 2008.
  • Research Careers in Academia. Invited talk to Undergraduate Biology Interest Group, The University of Chicago, 2008.
  • Current Directions for Behavioral Genetic Research on the Development of Antisocial Behavior. Keynote Speaker, Annual Research Day, Department of Psychology, University of Minnesota, 2006.
  • Using Behavior Genetics to Understand the Development of Antisocial Behavior.  Department of Psychiatry, University of California, San Diego, 2004.
  • The Genetic Basis of Substance Abuse. International Congress on Dual-Diagnosis: A Concept in Development, Zurich, Switzerland, 2003.

Other Activities

  • Editor, Behavior Genetics, Special issue on “Pathways between genes, brain, and behavior.” Scheduled for publication January, 2010.
  • Ad hoc reviewer, NIH, 2002- present.
  • Board Member, South Chicago Art Center, a community-based center for underprivileged children in the South Side of Chicago, 2008- present.